Effects of Mesotherapy
The effects of Mesotherapy
The local Effects
It is quite logical that product, depending solely on its composition, carries out its action in the place where, or at the level at which, it is injected
Local – regional effect
This refers to the deepest levels in the immediate area where the medicine is injected, duly reflected in the classic experiment of observing high concentrations of a medicine at the knee joint when it is injected superficially – intradermally (Mesotherapy) into the skin of the same
Regional effect
In some cases, it refers to the effects obtained in the specific metameric region corresponding to the injection area. In other cases in other cases, we inject the medicine at so-called “Trigger Points” in order to remedy the problem of a particular area.
General effect
Obviously, Mesotherapy injected medicines end up in the general circulatory system. Notwithstanding, it must be remembered that, on account of the specific characteristics of this methods of administration, and its capacity to act as a reservoir, its passage through aforesaid system in minimal, as has been demonstrated by Le Coz. The passing into the general circulatory system of the medicine administered in this manner is four times less than if it had been administered by IM. Therefore, any undesirable side effects are minimised.
Selection criteria with respect to the substances to be used in Mesotherapy
The medicines used in the Mesotherapy are selected empirically, either by simple and original extrapolation from the classic pharmacopoeia, or by clinical experimentation. Even so, before using any medicine mesotherapeutically, we need to make sure that it complies with a series of Criteria for use, given that, the simple fact that the medicine or drug in question is marked in an ampule format, does not necessarily mean that it can be validly used according to the mesotherapeutic practice. In fact, the majority of problems provoked by this technique are either as a result of administrating medicines that do not fulfil the essential 10 commandments that we deem to be the criteria for use, or because their presentation in the ampoule format sees us drop our guard and simply confide in their presentation in the ampoule format sees us drop our guard and simply confide in their condition as sterile for mesotherapeutic application.
When we speak of homeopathic Mesotherapy, we are stressing the large amount of the products that are available on the market as “homeopathic medicines in sterile ampoules”, which in no way accredits their capacity to be injected, and which, therefore, we must systematically discard from our therapeutic arsenal, given that they must in no way be used mesotherapeutically.
Consequently, all of the medicines that can be used in Mesotherapy must comply with the following criteria, validating their fitness for use:
- They can all be dissolved in water
- Hypotonic or hypertonic solutions must be prohibited. They give rise to ionic disorders at a cellular level, and possibly tissue damage
- Perfect tolerance in subcutaneous tissue (pH neutral)
We are not speaking here only about the absence of pain, an important question in terms of the acceptance of the technique by the patient, but that the medicines must not cause either local or regional irritation.
They must not provoke nodules, as for example in the repeated injections of insulin to which diabetics are subject.
The must not provoke tissue lysis, as happens with some corticoids which give rise to muscular and ligament lysis.
They must not give rise to abscesses. This can be put down more to an accident due to contamination that due to medicine itself. If the proper measures are taken, this condition is extremely rare in Mesotherapy.
- Total integration in the tissue
Certain protein compounds cannot be administered mesotherapeutically, given the fact that they are rejected by the tissues.
- The complete absence of allergies and hypersensitive phenomena
Allergies to medicines represent 50% of the iatrogenic pathology in Mesotherapy. In this sense, an in-depth interrogation concerning the patient’s medical history is essential, although in Mesotherapy it is extremely difficult to accurately diagnose the product that gives rise to such sensitivity, given that normally mixtures of several medicines are used, and we might be up against a case of crossed sensitivity among same.
- Never use oily vehicles
Avoid giving rise to “polyolic thrombosis”
We are referring here to some types of oily excipients. They are hydro soluble, but are very dense. We must make sure of their complete miscibility in another product which will act as a vector before the injection, and ensure that no opalescence or iridescence occurs in the syringe on looking into same when held up to the light.
- Perfect mutual compatibility:
- Total miscibility
- Always the same pH
- Neither precipitation nor opalescence
We will systematically discard any mixture in which we observe physical changes, precipitations, the forming of lumps, etc.
- The must never antagonise each other
Obviously, substances that cancel out the effects of each other must not be used.
- Perfect synergy of the associated medicines
Whenever we use a mixture of medicines we must make sure that effects of each one of the substances complement or boost that of the others
Acknowledged effectiveness